GLP-1 receptor agonists are a class of medications that mimic the action of the glucagon-like peptide-1 (GLP-1), a hormone involved in the regulation of glucose metabolism. These agonists bind to and activate the GLP-1 receptors in the body, leading to increased insulin secretion, reduced glucagon release, and slower gastric emptying. This helps to lower blood sugar levels in people with type 2 diabetes. Additionally, GLP-1 receptor agonists can promote weight loss and have cardiovascular benefits. They are usually administered as injections and are often used in combination with other diabetes medications to improve glycemic control. Examples of GLP-1 receptor agonists include exenatide, liraglutide, and semaglutide.
Recent studies have shed light on the role of GLP-1 receptor agonists (GLP-1RAs) in managing diabetes and obesity. With over 215,000 diabetes patients treated with GLP-1RAs, researchers sought to evaluate…